Since the effects of the previously identified SOCS proteins in the various types of cancer are very different, they analyzed Prof click to this web-site read more . Culig closer to SOCS-1 in prostate cancer cells He selected two more highly informative experiments in which the of the of the SOCS. In the cells in the cells and was one in which it has been reduced. Thus it was possible to show that SOCS-1 inhibits tumor growth by suppression of the proliferation of tumor cells. Particularly it was shown that SOCS-1 influence the synthesis of cyclin and CDK proteins, both of which help initiate proliferation.
After lung and colon cancer, prostate cancer is the form of the disease with the highest mortality rate for men. In the initial stage of development of tumors, however, offer both radiation therapy and surgical removal of tumors good chance for a successful treatment. While chemotherapy is more effective in later stages of development is hormone treatment currently the method of choice. This is Currently one of the main reasons for the occurrence and development of prostate cancer is the activation of receptors for male sex hormones on the prostate cells. In recent years has shown, however, increasing evidence that chronic inflammation factor factor. To get a better understanding of these relationships, the signaling pathways associated with the process being analyzed in detail.
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