IL – 11Ra is a target in bone metastasis, much less is known about its attributes, if any, in primary tumors of the bone to IL. Addressing – 11Ra as a potential molecular target in osteosarcoma, confirmed the authors, the protein expression and localization of IL – 11Ra in several mouse and human osteosarcoma cell lines.
Is not in a mouse model of orthotopic human osteosarcoma, the researchers found that the IL – 11Ra was only evident in the primary osteosarcoma and in its metastases but was absent from normal bone marrow and lungs.Over 400,000 Americans has multiple sclerosis and MS can be more than 2.5 million people are affected worldwide. MS an autoimmune disease in which the immune system reacts to individual multiple components of nerve cells insulating myelin. The effects of these immune-mediated attacks can made of relatively benign somewhat deactivation of to disastrous, as communication between brain and other parts the body sufficient interrupted. Peptimmune.
Peptimmune, be a privately , announced, announced that physicians have the first subscriber in a trial will evaluate the safety, to rate compatibility of handled, pharmacokinetics and pharmacodynamics on PI-2301 to patients with secondary progressive multiple sclerosis . CI-2301 is a novel peptide copolymer of used to treat multiple sclerosis and others autoimmune disorders.